The top 10 health conditions that have the greatest impact on Americans’ quality of life

10. Crohn’s Disease/Ulcerative Colitis — National Health Impact 2.7%

This chronic disease causes inflammation in the digestive tract. “Crohn’s affects your small intestine and the beginning of your large intestine.

09. Psychotic Disorder — National Health Impact 2.9%

People with psychotic disorders, including schizophrenia and delusional disorder, often have trouble maintaining a sense of reality.

08. Chronic Obstructive Pulmonary Disease (COPD) — National Health Impact 3.3%

A chronic inflammatory lung disease, COPD causes airflow from the lungs to be obstructed. The primary cause of COPD is cigarette smoking.

07. Alcohol Use Disorder — National Health Impact 3.3%

It is chronic relapsing brain disease characterized by compulsive alcohol use, loss of control over alcohol intake, and a negative emotional state when not using.

06. Substance Use Disorder — National Health Impact 3.4%

Also known as a drug use disorder, a substance use disorder involves an overuse of, or dependence on, a medication or toxin.

05. Type 2 Diabetes — National Health Impact 5.5%

In people with diabetes, blood sugar levels rise higher than normal. Type 2 diabetes is most common  caused by obesity and lack of physical activity.

04. Coronary Artery Disease — National Health Impact 7%

High blood pressure, high cholesterol, smoking and diabetes can all damage or injure the inner layer of coronary arteries.

03. High Cholesterol — National Health Impact 8.6%

When levels of cholesterol are too high, fatty deposits can begin to build up in blood vessels and arteries, restricting blood flow.

02. Major Depression — National Health Impact 9%

This frequently goes misdiagnosed or untreated, is a mental illness characterized by a constant sense of hopelessness and despair, making it difficult to work, sleep or eat.

01. Hypertension — National Health Impact 12.5%

Commonly known as high blood pressure, hypertension is a common disease in which blood flows through blood vessels or arteries, at higher than normal pressure.